this book constitutes the refereed proceedings of the 11th international conference on algorithms and computation, isaac 2000, held in taipei, taiwan in december 2000.the 46 revised papers presented together with an invited paper were carefully reviewed and selected from 87 submissions. the papers are organized in topical sections on algorithms and data structures; combinatorial optimization; approximation and randomized algorithms; graph drawing and graph algorithms; automata, cryptography, and complexity theory; parallel and distributed algorithms; computational geometry; and computational biology.