The Mystery of Miz Arnette is set in Oklahoma's devastating Dust Bowl. The time is 1934 when Baby Face Nelson and Pretty Boy Floyd along with their gangs roamed the territory. Out of the desolate nowhere arrives Miz Arnette to rent the room that had been advertised and leased four months ago. With the family farm at stake and desperate for the additional income, young Floy Kate strikes a deal and takes in the intriguing stranger that would forever change her life.