Name: The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation (en Inglés)
Price: 173.42 USD
Availability: InStock
Author: Rossetti, Carlo ; Peri, Francesco
ISBN: 9783030563189

portada The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Rossetti, Carlo ; Peri, Francesco

Idioma

Inglés

N° páginas

174

Encuadernación

Tapa Dura

Dimensiones

23.4 x 15.6 x 1.3 cm

Peso

0.44 kg.

ISBN13

9783030563189

Categorías

Inmunología
Microbiología médica y virología
Bioquímica

The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation (en Inglés)

Rossetti, Carlo ; Peri, Francesco (Autor) · Springer · Tapa Dura

Libro Físico

$ 173.42

$ 266.81

Ahorras: $ 93.38

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Reseña del libro "The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation (en Inglés)"

TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer's diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis andneuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4.