Name: Diffusion-Reaction Modeling, Nonlinear Dynamics, Feedback, Bifurcation and Chaotic Behavior (en Inglés)
SKU: 62590964
Price: 109.90 USD
Availability: InStock
Author: Ibrahim Mustafa
ISBN: 9783639864205

portada Diffusion-Reaction Modeling, Nonlinear Dynamics, Feedback, Bifurcation and Chaotic Behavior (en Inglés)

Diffusion-Reaction Modeling, Nonlinear Dynamics, Feedback, Bifurcation and Chaotic Behavior (en Inglés)

Formato

Libro Físico

Editorial

Scholars' Press

Autor

Ibrahim Mustafa

Idioma

Inglés

N° páginas

236

Encuadernación

Tapa Blanda

ISBN13

9783639864205

Diffusion-Reaction Modeling, Nonlinear Dynamics, Feedback, Bifurcation and Chaotic Behavior (en Inglés)

Ibrahim Mustafa (Autor) · Scholars' Press · Tapa Blanda

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Reseña del libro "Diffusion-Reaction Modeling, Nonlinear Dynamics, Feedback, Bifurcation and Chaotic Behavior (en Inglés)"

The disturbances and abnormalities occurring in the components of the Acetylcholine (ACh) neurocycle are considered one of the main features of cholinergic sicknesses like Parkinson's and Alzheimer's diseases. A fundamental understanding of the ACh neurocycle is therefore very critical in order to design drugs that keep the ACh concentrations in the normal physiological range. In this dissertation, a novel two-enzyme-two-compartment model is proposed in order to explore the bifurcation, dynamics, and chaotic characteristics of the ACh neurocycle. The model takes into consideration the physiological events of the choline uptake into the presynaptic neuron and the ACh release in the postsynaptic neuron. In order to approach more realistic behavior, two complete kinetic mechanisms for enzymatic processes pH-dependent are built: the first mechanism is for the hydrolysis reaction catalyzed by the acetylcholinesterase (AChE) and the other is for the synthesis reaction catalyzed by the cholineacetyltransferase (ChAT).