Name: Drug-Drug Interactions (en Inglés)
SKU: 54771517
Price: 64.01 USD
Availability: InStock
Author: Hyun Kim, Dong ; Lee, Sangkyu

portada Drug-Drug Interactions (en Inglés)

Formato

Libro Físico

Editorial

Mdpi AG

Autor

Hyun Kim, Dong ; Lee, Sangkyu

Idioma

Inglés

N° páginas

242

Encuadernación

Tapa Dura

Dimensiones

24.4x17x2.1 cm

Peso

0.72 kg.

ISBN13

9783036520353

Categorías

Ciencia: cuestiones generales

Drug-Drug Interactions (en Inglés)

Hyun Kim, Dong ; Lee, Sangkyu (Autor) · Mdpi AG · Tapa Dura

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Reseña del libro "Drug-Drug Interactions (en Inglés)"

Drug-drug interactions (DDIs) cause a drug to affect other drugs, leading to reduced drug efficacy or increased toxicity of the affected drug. Some well-known interactions are known to be the cause of adverse drug reactions (ADRs) that are life threatening to the patient. Traditionally, DDI have been evaluated around the selective action of drugs on specific CYP enzymes. The interaction of drugs with CYP remains very important in drug interactions but, recently, other important mechanisms have also been studied as contributing to drug interaction including transport- or UDP-glucuronyltransferase as a Phase II reaction-mediated DDI. In addition, novel mechanisms of regulating DDIs can also be suggested. In the case of the substance targeted for interaction, not only the DDIs but also the herb-drug or food-drug interactions have been reported to be clinically relevant in terms of adverse side effects. Reporting examples of drug interactions on a marketed drug or studies on new mechanisms will be very helpful for preventing the side effects of the patient taking these drugs. This Special Issue aims to highlight current progress in understanding both the clinical and nonclinical interactions of commercial drugs and the elucidation of the mechanisms of drug interactions.