portada Excitatory Amino Acids and Epilepsy (en Inglés)

Excitatory Amino Acids and Epilepsy (en Inglés)

Formato

Libro Físico

Autor

Robert Schwarcz

Yehezkel Ben-Ari

Editorial

Springer

Idioma

Inglés

N° páginas

735

Encuadernación

Tapa Blanda

Dimensiones

25.4x17.8x3.8 cm

Peso

1.28 kg.

ISBN13

9781468479737

Categorías

Bioquímica

Excitatory Amino Acids and Epilepsy (en Inglés)

Robert Schwarcz (Autor) · Yehezkel Ben-Ari (Autor) · Springer · Tapa Blanda

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Reseña del libro "Excitatory Amino Acids and Epilepsy (en Inglés)"

Human epilepsy is a major public health problem affecting approximately 2 persons per 1000. It is particularly frequent in ohildren where convul- sions may lead to brain damage and subsequent seizure activity in adulthood. Temporal lobe epilepsy (synonyms include limbic epilepsy. psychomotor epilepsy and complex partial epilepsy) is the most devastating form of epilepsy in the adult population since: a) it is often extremely resistant to currently available anticonvulsant drugs (i.e -- it is more resistant than tonico-clonic or grand mal seizures) and b) it includes loss of consciousness. thereby limiting performance of many normal functions and leaving the individual susceptible to bodily injury. It is also associated with nerve cell loss. in particular in the hippocampus and other structures of the temporal lobes. In order to promote an appropriate therapy it is essential to understand the etiology of seizures and its relationship to brain damage. Basic research on epilepsy also provides a very useful vehicle to learn about the way the brain functions under normal conditions. For instance. much of our present understanding of the mechanisms of action of GABA and benzo- diazepines. control of neuronal activity. etc. has been derived from such stUdies.