Name: Exploring Drug Delivery to the Peritoneum
SKU: 64794067
Price: 187.44 USD
Availability: InStock
Author: Ranjita Shegokar
ISBN: 9783031316968

portada Exploring Drug Delivery to the Peritoneum

Exploring Drug Delivery to the Peritoneum

Formato

Libro Físico

Editorial

Springer International Publishing AG

Autor

Ranjita Shegokar

Año

2024

N° páginas

242

Encuadernación

Tapa Blanda

Dimensiones

23.5x15.5 cm

ISBN13

9783031316968

Exploring Drug Delivery to the Peritoneum

Ranjita Shegokar (Autor) · Springer International Publishing AG · Tapa Blanda

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Reseña del libro "Exploring Drug Delivery to the Peritoneum"

The Peritoneal cavity (PC) is the key metastatic site for intra-abdominal malignancies (e.g., GI tract and rectal cancer). PC sites can be used to target several other diseases where lymphatic drug delivery is desired without dumping large amounts of the drug. Till recently, it was thought that treatment with curative intent was impossible but that was challenged by the introduction of cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC), and PIPAC (pressurized intraperitoneal aerosol chemotherapy). Recently, a growing number of preclinical and clinical studies advocate intraperitoneal (IP) chemotherapy as an alternative post-operative therapy for cancer. Although their effectiveness has been proven both experimentally and clinically, there is still little understanding of the role of drug delivery systems (DDS) in targeting drugs in the intraperitoneal (IP) cavity. There are two main challenges one posed by IP cavity where the residence time of a small molecular weight drug (