Name: Formulation and Evaluation of Albendazole Tablet (en Inglés)
SKU: 25766418
Price: 42.94 USD
Availability: InStock
Author: Sandhya Chaurasia; Anshuli Sharma; Suneel Kumar Vasireddy
ISBN: 9783659192920

portada Formulation and Evaluation of Albendazole Tablet (en Inglés)

Formulation and Evaluation of Albendazole Tablet (en Inglés)

Formato

Libro Físico

Editorial

Lap Lambert Academic Publishing

Autor

Sandhya Chaurasia; Anshuli Sharma; Suneel Kumar Vasireddy

Tema

FTIR, Floating drug delivery systems (FDDS), In-vitro byouance properties

Año

2012

Idioma

Inglés

N° páginas

120

Encuadernación

Tapa Blanda

ISBN

3659192929

ISBN13

9783659192920

Categorías

Farmacología

Formulation and Evaluation of Albendazole Tablet (en Inglés)

Sandhya Chaurasia; Anshuli Sharma; Suneel Kumar Vasireddy (Autor) · Lap Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Formulation and Evaluation of Albendazole Tablet (en Inglés)"

The objective of this research work was to formulate and evaluate the floating drug delivery system containing Albendazole, an anthelmintic drug, using different polymers and to optimize the best formulation. Different excipients were tested for their compatibility with Albendazole by the FTIR studies. Present study has demonstrated the successful utilization of technique of FT IR to assesst he compatibility of Albendazole with the excipients used in the development of floating drug delivery system of Albendazole. Based on the results of FT-IR studies, majority of the excipients were found to be compatible with Albendazole which were then used in the preparation of Albendazole floating tablets. Albendazole tablets were prepared by wet granulation technique using HPMC, HPMC K4M and chitosan as polymers, stearic acid, citric acid, lactose and gas generating agent such as sodium bicarbonate were taken as independent variables. It was then evaluated by using USP-II (Paddle) apparatus containing 0.1 N HCl as a dissolution media. The release mechanisms of Albendazole from floating tablet were evaluated by the n value of Krosmeyer Peppas model.