Name: Genetic Immunization (en Inglés)
SKU: 25620487
Price: 153.65 USD
Availability: InStock
Author: Bot, Adrian ; Bona, Constantin A.
ISBN: 9781441933270

portada Genetic Immunization (en Inglés)

Formato

Libro Físico

Autor

Adrian Bot

Constantin A. Bona

Editorial

Springer

Año

2010

Idioma

Inglés

N° páginas

180

Encuadernación

Tapa Blanda

Dimensiones

25.4x17.8x1.1 cm

Peso

0.35 kg.

ISBN

1441933271

ISBN13

9781441933270

Categorías

Salud pública y medicina preventiva
Genética médica
Inmunología

Genetic Immunization (en Inglés)

Adrian Bot (Autor) · Constantin A. Bona (Autor) · Springer · Tapa Blanda

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Reseña del libro "Genetic Immunization (en Inglés)"

Wolf's discovery demonstrating that a reporter gene is expressed in myocytes subsequent to injection of naked DNA, was exploited by immunologists and vaccinologists to develop a new generation of vaccines. This observation galvanized the research and in a short lapse of time, an oceanic volume of knowledge has been accumulated. The research carried out in a variety of animal models showed the efficacy of genetic immunization against viruses, bacteria, and some parasites by the ability to induce a strong priming effect resulting from long-lasting persistence of plasmid as episomes. Furthermore, it was demonstrated that newborn or infant immune unresponsiveness to classical vaccines can be corrected by genetic immunization. The applications of genetic immunization for prophylaxis of infections was extended to immunotherapy, namely, cancerous, auto- immune, and allergic diseases. Immunologists have provided pertinent information on the cellular basis of the immune responses elicited by genetic immunization, and molecular biologists have established the molecular basis of intrinsic adjuvant properties of plasmids.