Name: Glycosaminoglycans and Proteoglycans
SKU: 52955723
Price: 62.84 USD
Availability: InStock
Author: Barbara Mulloy

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portada Glycosaminoglycans and Proteoglycans

Formato

Libro Físico

Autor

Barbara Mulloy

Encuadernación

Tapa Blanda

ISBN13

9783038428350

Categorías

Farmacología

Glycosaminoglycans and Proteoglycans

Barbara Mulloy (Autor) · · Tapa Blanda

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Reseña del libro "Glycosaminoglycans and Proteoglycans"

Proteoglycans (PGs) are glycoconjugates in which a protein or peptide core is substituted with polysaccharide chains known as glycosaminoglycans (GAGs). The GAG sidechains carry a significant proportion of the functionality of PGs, interacting with many proteins to form structural units in the extracellular matrix and to modulate the transport and signalling of small proteins acting as morphogens, growth factors and cytokines. Purified GAGs such as heparin and hyaluronan are in common use as therapeutic agents, with many more PG-based natural products, synthetic and semi-synthetic mimetics on the way; in addition, potential therapeutic strategies involving PG/GAG biosynthesis and degradation as targets are currently in development.