portada Gram-negative bacilli isolated from the hospital environment (en Inglés)

Gram-negative bacilli isolated from the hospital environment (en Inglés)

Formato

Libro Físico

Autor

Manel Debabza

Abdelbasset Mechai

Editorial

Our Knowledge Publishing

Idioma

Inglés

N° páginas

172

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x1 cm

Peso

0.26 kg.

ISBN13

9786207044122

Categorías

Microbiología (no médica)

Gram-negative bacilli isolated from the hospital environment (en Inglés)

Manel Debabza (Autor) · Abdelbasset Mechai (Autor) · Our Knowledge Publishing · Tapa Blanda

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Reseña del libro "Gram-negative bacilli isolated from the hospital environment (en Inglés)"

In this study, 306 Gram-negative bacilli (GNB) strains were isolated from the hospital environment, 74.51% of them enterobacteria. Antibiotic susceptibility testing revealed resistance to various families of antibiotics, in particular β-lactam antibiotics, although imipenem, aminoglycosides and fluoroquinolones were remarkably effective. Extended-spectrum beta-lactamase (ESBL) detection tests were used to characterize 114 strains of ESBL-producing Enterobacteriaceae (EBLSE). Analysis of plasmid profiles showed that multi-resistant strains host 1 to 4 plasmids ranging from 1Kb to 170Kb. Conjugation experiments showed co-transfer of gentamicin and cotrimoxazole resistance to plasmids of 10Kb, 20Kb, 125Kb or 165Kb. PCR of transconjugating strains detected the bla CTX-M-1, bla TEM and bla SHV genes, as well as the qnrB genes. This study shows that the hospital environment is contaminated by multi-resistant BGN, particularly EBLSE, and that it can be a potential source of epidemics, prompting recommendations to be made within health facilities.