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Matrix Metalloproteinases and Timps (Protein Profiles) (en Inglés)
J. F. Woessner; Fred Woessner; Hideaki Nagase (Autor)
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Oxford University Press
· Tapa Blanda
Matrix Metalloproteinases and Timps (Protein Profiles) (en Inglés) - J. F. Woessner; Fred Woessner; Hideaki Nagase
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Reseña del libro "Matrix Metalloproteinases and Timps (Protein Profiles) (en Inglés)"
The matrix metalloproteinases (MMPs) are a large family of enzymes that breakdown different components of the extracellular matrix. Their catalytic activity is dependent a metal ion, usually zinc. This issue of the Protein Profiles covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological roles of all the currently identified MMPs. The action of these enzymes must be carefully regulated. One way the cell does this, is by releasing inhibitory molecules known as tissue inhibitors of metalloproteinases (TIMPs). This volume contains information on the sequences, three-dimensional structures, and biological roles of the 4 known classes of TIMP. Matrix metalloproteinases will therefore be an invaluable source of data for all researchers interested in MMPs and TIMPs.
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