Name: Optimal Design for Nonlinear Response Models (en Inglés)
SKU: 3830761
Price: 256.16 USD
Availability: InStock
Author: Fedorov, Valerii V. ; Leonov, Sergei L.
ISBN: 9781439821510

portada Optimal Design for Nonlinear Response Models (en Inglés)

Optimal Design for Nonlinear Response Models (en Inglés)

Formato

Libro Físico

Autor

Valerii V. Fedorov

Sergei L. Leonov

Editorial

CRC Press

Año

2011

Idioma

Inglés

N° páginas

402

Encuadernación

Tapa Dura

Dimensiones

23.6x15.7x2.5 cm

Peso

0.68 kg.

ISBN

1439821518

ISBN13

9781439821510

Categorías

Farmacología
Probabilidad y estadística

Optimal Design for Nonlinear Response Models (en Inglés)

Valerii V. Fedorov (Autor) · Sergei L. Leonov (Autor) · CRC Press · Tapa Dura

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Reseña del libro "Optimal Design for Nonlinear Response Models (en Inglés)"

Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors' many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of the key ideas, using linear models as examples. Applying the linearization in the parameter space, it then covers nonlinear models and locally optimal designs as well as minimax, optimal on average, and Bayesian designs. The authors also discuss adaptive designs, focusing on procedures with non-informative stopping. The common goals of experimental design--such as reducing costs, supporting efficient decision making, and gaining maximum information under various constraints--are often the same across diverse applied areas. Ethical and regulatory aspects play a much more prominent role in biological, medical, and pharmaceutical research. The authors address all of these issues through many examples in the book.