Name: Parkinson's Disease: Genetics and Pathogenesis (en Inglés)
SKU: 57729678
Price: 71.39 USD
Availability: InStock
Author: Lesage, Suzanne ; Trinh, Joanne

portada Parkinson's Disease: Genetics and Pathogenesis (en Inglés)

Parkinson's Disease: Genetics and Pathogenesis (en Inglés)

Formato

Libro Físico

Editorial

Mdpi AG

Autor

Lesage, Suzanne ; Trinh, Joanne

Idioma

Inglés

N° páginas

238

Encuadernación

Tapa Dura

Dimensiones

24.4x17x2.1 cm

Peso

0.71 kg.

ISBN13

9783036588803

Categorías

Biología, ciencias de la vida

Parkinson's Disease: Genetics and Pathogenesis (en Inglés)

Lesage, Suzanne ; Trinh, Joanne (Autor) · Mdpi AG · Tapa Dura

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Reseña del libro "Parkinson's Disease: Genetics and Pathogenesis (en Inglés)"

Parkinson's disease (PD) is the second-most common neurodegenerative disease, currently affecting more than 10 million people worldwide. There is currently no identified treatment and only symptomatic relief can be offered. The disease has clinical and pathological definitions through its cardinal motor manifestations and substantia nigra neuronal loss associated with intraneuronal Lewy bodies, respectively. The molecular mechanisms that lead to neurodegeneration remain elusive. It is becoming increasingly apparent that genetic factors contribute to its complex pathogenesis, with 90 loci from genome-wide association studies and many monogenic causes unraveled in the past years. The knowledge acquired from their protein products revealed pathways of neurodegeneration that Mendelian and sporadic Parkinsonism may share. These pathways include synaptic, lysosomal, mitochondrial, and immune-mediated mechanisms of pathogenesis. This Special Issue, "Parkinson's Disease: Genetics and Pathogenesis", collected 12 high-quality papers, including 7 original research articles and 5 reviews, that seek to deepen the knowledge of multiple aspects related to Parkinsonism.