Name: Phytochemical and Neuroprotective evaluation of Pedalium murex Linn Leaf (en Inglés)
Price: 68.91 USD
Availability: InStock
Author: Swaminathan, Gomathi ; Byran, Gowramma ; Rajagopal, Kalirajan
ISBN: 9786200300348

portada Phytochemical and Neuroprotective evaluation of Pedalium murex Linn Leaf (en Inglés)

Formato

Libro Físico

Autor

Gomathi Swaminathan

Gowramma Byran

Kalirajan Rajagopal

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

128

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.8 cm

Peso

0.20 kg.

ISBN13

9786200300348

Categorías

Farmacología

Phytochemical and Neuroprotective evaluation of Pedalium murex Linn Leaf (en Inglés)

Gomathi Swaminathan (Autor) · Gowramma Byran (Autor) · Kalirajan Rajagopal (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Phytochemical and Neuroprotective evaluation of Pedalium murex Linn Leaf (en Inglés)"

This book deals with the phytochemical characterization and neuroprotective evaluation of Pedalium murex Linn leaves against bacterial cell wall content Lipopolysaccharide (LPS)-induced endotoxemia in rats. Huge number of behavioural changes are associated with Neurodegenerative diseases (ND) such as depression, anxiety, memory loss, stress and so on. Two compounds were isolated from 90% v/v of ethanol extract of Pedalium murex Linn (EEPM) named as PM I, PM II. Spectral data of isolated compounds strongly suggested that PM I showed the structural similarities with 4 , 5, 7- trihydroxy flavone may be Apigenin and PM II showed the structural similarities with 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one which may have the presence of kaempferol. The data of our present study revealed that LPS significantly decreases the general behavior and increases the memory loss, anxiety & depression which was recovered EEPM treated rats. EEPM attenuated or completely abolished the symptoms of depression and anxiety.We may conclude that EEPM may be a potential candidate for LPS-induced brain damage which may be attributed to the presence of potent antioxidants in EEPM.