Name: Polyglobulia Vaquez (en Inglés)
SKU: 58341569
Price: 62.06 USD
Availability: InStock
Author: Bouatay, Amina ; Ben Sayed, Nesrine ; Dardour, Saoussen
ISBN: 9786205294697

Formato

Libro Físico

Autor

Amina Bouatay

Nesrine Ben Sayed

Saoussen Dardour

Editorial

Our Knowledge Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x0.4 cm

Peso

0.10 kg.

ISBN13

9786205294697

Categorías

Biología, ciencias de la vida

Polyglobulia Vaquez (en Inglés)

Amina Bouatay (Autor) · Nesrine Ben Sayed (Autor) · Saoussen Dardour (Autor) · Our Knowledge Publishing · Tapa Blanda

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Reseña del libro "Polyglobulia Vaquez (en Inglés)"

Vaquez polycythemia (PV) is a myeloproliferative neoplasm resulting from clonal expansion of a pluripotent hematopoietic stem cell, causing proliferation of myeloid tissue predominantly in the erythrocyte lineage. It is characterized by an increase in total erythrocyte mass and hemoglobin without excessive stimulation by erythropoietin. Its incidence is low (2 to 3 cases per 100,000 inhabitants/year). The initial presentation is often pauci symptomatic. In some patients the occurrence of a thrombotic event or symptoms related to hyperviscosity syndrome leads to the diagnosis of PV.The discovery of the JAK2 V617F mutation has completely changed the diagnosis of PV and has allowed not only a better understanding of the pathophysiological mechanisms, but also the development of a targeted molecular therapy associated with an efficient molecular monitoring.