Name: Radiation Damage in Biomolecules and Cells (en Inglés)
SKU: 57896523
Price: 99.54 USD
Availability: InStock
Author: Ballarini, Francesca ; Carante, Mario Pietro

portada Radiation Damage in Biomolecules and Cells (en Inglés)

Radiation Damage in Biomolecules and Cells (en Inglés)

Formato

Libro Físico

Editorial

Mdpi AG

Autor

Ballarini, Francesca ; Carante, Mario Pietro

Idioma

Inglés

N° páginas

398

Encuadernación

Tapa Dura

Dimensiones

24.4x17x3.2 cm

Peso

1.05 kg.

ISBN13

9783036574875

Categorías

Biología, ciencias de la vida

Radiation Damage in Biomolecules and Cells (en Inglés)

Ballarini, Francesca ; Carante, Mario Pietro (Autor) · Mdpi AG · Tapa Dura

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Reseña del libro "Radiation Damage in Biomolecules and Cells (en Inglés)"

The papers collected in this Special Issue deal with the effects of ionizing radiation at molecular and cellular levels, as well as possible applications in medicine and radiation protection. In particular, some works analysed the early stages of the interaction between ionizing radiation and DNA focusing on DNA cluster damage, which is widely considered as an important step towards subsequent endpoints. Other studies investigated the consequences of hypoxia on the evolution of the initial DNA damage, and one work analysed genome-wide DNA alterations in irradiated human cells. Concerning radiation therapy, the response of cancer cells to different radiation types was characterized both in vitro and in vivo, and possible strategies to enhance such response were investigated; furthermore, FLASH radiotherapy was reviewed. In the framework of cancer therapy side effects, the consequences of high doses on gene expression in healthy cells were analyzed, and the RBE (Relative Biological Effectiveness) for late effects in the central nervous system was predicted by the BIANCA biophysical model. Finally, the protective role of melatonin and Vitamin D, as well as hypothermia, was reviewed, valine radiolysis was investigated, the changes in radio-sensitivity of embrios during the early developmental stages of the preimplantation were analyzed, and epigenetic modifications induced by ionizing radiation were reviewed.