portada receptor/ligand sorting along the endocytic pathway (en Inglés)

receptor/ligand sorting along the endocytic pathway (en Inglés)

Formato

Libro Físico

Autor

Jennifer J. Linderman

Douglas A. Lauffenburger

Editorial

Springer

Año

1989

Idioma

Inglés

N° páginas

164

Encuadernación

Tapa Blanda

Dimensiones

23.4x15.6x1 cm

Peso

0.26 kg.

ISBN

354050849x

ISBN13

9783540508496

Categorías

Álgebra
Matemáticas aplicadas

receptor/ligand sorting along the endocytic pathway (en Inglés)

Jennifer J. Linderman (Autor) · Douglas A. Lauffenburger (Autor) · Springer · Tapa Blanda

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Reseña del libro "receptor/ligand sorting along the endocytic pathway (en Inglés)"

This research monograph focuses on a biomolecular separation process that occurs within most cells. Two types of molecules, receptors and ligands, are separated and routed along different intracellular pathways; this is a critical step in the process of receptor-mediated endocytosis. The development of an understanding of the basic mechanisms of this separation process is presented, with an emphasis on discovering the fundamental and measurable parameters that influence the event. Mathematical models of sorting are evaluated to predict the range of possible outcomes. These are compared with a variety of experimental data on different receptor/ligand systems. In addition, the influence of the separation on overall receptor/ligand processing dynamics is discussed. The book is intended for both biomathematicians and biologists. It is not necessary to understand the details of the model equations and their solution in order to test the models experimentally. The analysis suggests experiments that might be done to further investigate the sorting process and the text details methods for analyzing these experimental results.