Name: redox proteomics: from protein modifications to cellular dysfunction and diseases
SKU: 10772164
Price: 312.70 USD
Availability: InStock
Author: isabella dalle-donne, andrea scaloni, d. allan butterfield
ISBN: 9780471723455

portada redox proteomics: from protein modifications to cellular dysfunction and diseases

redox proteomics: from protein modifications to cellular dysfunction and diseases

Formato

Libro Físico

Editorial

wiley-interscience

Autor

isabella dalle-donne, andrea scaloni, d. allan butterfield

N° páginas

944.00

ISBN

0471723452

ISBN13

9780471723455

Categorías

Microbiología (no médica)

redox proteomics: from protein modifications to cellular dysfunction and diseases

Isabella Dalle-Donne, Andrea Scaloni, D. Allan Butterfield (Autor) · wiley-interscience · Libro Físico

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Reseña del libro "redox proteomics: from protein modifications to cellular dysfunction and diseases"

substantial evidence suggests that oxidative and nitrosative changes in the proteins that make up human tissue contribute to the pathogenesis and / or progression of most human diseases. the field of redox proteomics seeks to characterize these oxidative / nitrosative modifications and to find new biomarkers for these changes in an effort to facilitate diagnosis and treatment of ageing-related and inflammatory diseases. this comprehensive reference book, written and edited by internationally known scientists from research institutions, hospitals, and universities worldwide, presents pioneering studies determining the development of redox proteomics. it moves from describing the methodologies for identification and structural characterization of proteins affected by oxidative/nitrosative modifications, including mass spectrometry and electrophoretic methods; to discussing cellular aspects of protein oxidation in different cell models; and ends with a section focusing on the pathological aspects of protein oxidation and their implications for treating selected human diseases such as cardiovascular disease, diabetes, pre-eclampsia, and alzheimer ` s disease.