Name: tachykinins (en Inglés)
SKU: 25916971
Price: 286.17 USD
Availability: InStock
Author: Holzer, Peter
ISBN: 9783540206903

Formato

Libro Físico

Ilustrado por

Peter Holzer

Editorial

Springer

Autor

Holzer, Peter

Año

2004

Idioma

Inglés

N° páginas

569

Encuadernación

Tapa Dura

Dimensiones

23.4x15.6x3.2 cm

Peso

0.99 kg.

ISBN

3540206906

ISBN13

9783540206903

Categorías

Farmacología
Neurología y neurofisiología clínicas
Neurociencias
Jardinería

tachykinins (en Inglés)

Peter Holzer (Ilustrado por) · Springer · Tapa Dura

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Reseña del libro "tachykinins (en Inglés)"

More than 70 years have elapsed since U. S. von Euler and I. H. Gaddum dis- covered an unidentified depressor substance in the brain and gut. The effects of the powdery extracts were marked as 'P' on the kymograph tracings, and the nondescript name of 'substance P' still carries the breath of this adventurous period. In the 1960s, substance P returned in another disguise, staging as a hypothalamic peptide that causes copious salivary secretion (see chapter by F. Lembeck and I. Donnerer). This time, though, the mysterious substance was tracked down by S. E. Leeman and her collaborators as an undecapeptide, after it had eluded its identification for some 40 years. Substance P turned out to be the mammalian counterpart of a family of peptides which had been extracted from amphibian and nonvertebrate species and which had been given the name 'tachykinins' by V. Erspamer. Soon novel members of this peptide family were discovered, and in mammals substance P was joined by neurokinin A and neu- rokinin B. The presence of tachykinins in frog skin as well as in venoms and toxins of microbes and arachnids raises the possibility that these peptides re- present an old system of biological weapons that have been transformed to a particular messenger system in mammals.