Name: the scid mouse: characterization and potential uses (en Inglés)
SKU: 24701029
Price: 109.12 USD
Availability: InStock
Author: Bosma, Melvin J. ; Phillips, Robert A. ; Schuler, Walter

portada the scid mouse: characterization and potential uses (en Inglés)

the scid mouse: characterization and potential uses (en Inglés)

Formato

Libro Físico

Ilustrado por

Editorial

Autor

Bosma, Melvin J. ; Phillips, Robert A. ; Schuler, Walter

Año

2011

Idioma

Inglés

N° páginas

263

Encuadernación

Tapa Blanda

Dimensiones

24.4x17x1.5 cm

Peso

0.45 kg.

ISBN

3642749763

ISBN13

9783642749766

Categorías

Inmunología
Hacer frente a las alergias, incluidas las alimentarias

the scid mouse: characterization and potential uses (en Inglés)

Melvin J. Bosma (Ilustrado por) · Robert A. Phillips (Ilustrado por) · Walter Schuler (Ilustrado por) · Springer · Tapa Blanda

Libro Nuevo Importado

Envío: 16 a 23 días háb.

$ 218.24$ 109.12

-50%

Costos de importación incluídos en el precio ✅

Libro Nuevo

Quedan más de 100 unidades

$ 109.12

Llega entre el 18 Sep y el 01 Oct a Quito, Pichincha. Seleccionar ubicación

Agregar a lista de deseos

Reseña del libro "the scid mouse: characterization and potential uses (en Inglés)"

During routine genetic screening of several immunoglobulin heavy chain congenic mouse strains in 1980, one of us (MB) was surprised to find that several mice in the C.B-17IIcr strain, which was being maintained in a specific-pathogen-free facility of the Fox Chase Cancer Center (Philadelphia, PA), did not express serum immunoglobulin of the appropriate allotype. Fearing an error in the breeding of these mice, the sera of the suspect mice were screened for other allotypes. When these tests revealed a complete absence of serum immunoglobulin, it became apparent that a mutation had probably occurred in the C.B-17IIcr line. Further analysis revealed that a single breeding pair was respon- sible for all of the immunoglobulin negative mice and that the defect showed recessive inheritance. Thus was the C.B-17/Icr scid or severe combined immune deficient (scid) mouse discovered. Although it has taken most animal facilities several years to breed scid mice of high quality for experimental purpose, it was clear by 1987 that many investigators were beginning to exploit the unique qualities of the scid mouse for studies in several areas.