portada VEGF Gene Polymorphisms in Behçet Disease (en Inglés)

VEGF Gene Polymorphisms in Behçet Disease (en Inglés)

Formato

Libro Físico

Autor

Kamel Hamzaoui

Agnès Hamzaoui

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

100

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x0.6 cm

Peso

0.16 kg.

ISBN13

9786202524339

Categorías

Empresa y gestión

VEGF Gene Polymorphisms in Behçet Disease (en Inglés)

Kamel Hamzaoui (Autor) · Agnès Hamzaoui (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "VEGF Gene Polymorphisms in Behçet Disease (en Inglés)"

Behçet's disease (BD) is currently considered an "auto-inflammatory disease" triggered by infection and environmental factors in genetically predisposed individuals. Although the disease is characterized by recurrent oral and genital aphthous ulcers and ocular involvement, it can affect multiple organ systems. Complex aphthosis is characterized by recurrent oral and/or genital aphthous ulcers. It is important to evaluate the patient with complex aphthosis for Behçet's disease and related systemic disorders. Helper T (Th) cells, cytokines, neutrophils and antigen-presenting cells are particularly important in the immuno-pathogenesis of BD. Along with human leukocyte antigen gene encoding B*51 (HLA‐B*51) and areas including the major histocompatibility complex class I, genome‐wide association studies have recognized numerous other BD susceptibility genes including vascular endothelial growth factor (VEGF) polymorphism. VEGF takes on major importance essentially at the level of the barriers between the endothelium and the various vital systems during the inflammatory process as inflammation is a stimulus for VEGF production.