Name: X-Ray Structure Analysis of Bio-Macromolecular Crystals. Practical Methods and Basic Theory
SKU: 65870007
Price: 182.39 USD
Availability: InStock
Author: Dr Akio Takenaka;Dr Wayne Dawson;Dr Toshiyuki Chatake;Dr Tomoko Sunami;Dr Takashi ) Kumasaka;Dr Jiro Kondo;Dr Ella Morishita

portada X-Ray Structure Analysis of Bio-Macromolecular Crystals. Practical Methods and Basic Theory

X-Ray Structure Analysis of Bio-Macromolecular Crystals. Practical Methods and Basic Theory

Formato

Libro Físico

Editorial

Oxford University Press

Autor

Dr Akio Takenaka;Dr Wayne Dawson;Dr Toshiyuki Chatake;Dr Tomoko Sunami;Dr Takashi ) Kumasaka;Dr Jiro Kondo;Dr Ella Morishita

Colección

International Union of Crystallography Texts on Crystallography

Año

2026

N° páginas

240

Encuadernación

Tapa Dura

Dimensiones

24.6x18.9 cm

ISBN13

9780198933595

X-Ray Structure Analysis of Bio-Macromolecular Crystals. Practical Methods and Basic Theory

Dr Akio Takenaka;Dr Wayne Dawson;Dr Toshiyuki Chatake;Dr Tomoko Sunami;Dr Takashi ) Kumasaka;Dr Jiro Kondo;Dr Ella Morishita (Autor) · Oxford University Press · Tapa Dura

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Reseña del libro "X-Ray Structure Analysis of Bio-Macromolecular Crystals. Practical Methods and Basic Theory"

The aim of this textbook is to provide a complete understanding of X-ray structural analysis techniques, why the complex operations are necessary, what the principles behind them are, and what precautions should be taken through such practices.

Since the late 19th century, X-ray structural studies have forged ahead through technological progress and the creative ingenuity of researchers. As high intensity X-ray sources and increased speed and sensitivity of the detectors have emerged, it''s now possible to image the atomic structure of complex bio-macromolecules, the orbital electron density of small molecules, and to even follow the dynamical behavior of bio-macromolecules. Textbooks from which junior researchers can grasp the current art have not kept pace with the technological developments and diversification of the field. X-ray studies of bio-macromolecules require a broad understanding of the theory and practical methodologies. A project can include isolating, crystalizing, and adjudicating suitable samples, obtaining and analysing the X-ray data, and finally publishing the results in a standard format. Early decisions in a project can become pitfalls that swallow the unwary. It is increasingly essential to become adept at managing both proteins and nucleic acids. Whereas software is available to help in the critical problem of resolving the phase, expedience often encourages treating such tools as a black-box. The aim here is to help navigate the researcher through these multifarious issues. The book is intended to serve as a "companion" to experimentalists. It is divided into a general overview of X-ray structural analysis techniques (chapters 1-2) and a detailed discussion (chapters 3-16) that begins with the preparation of proteins and (uniquely) nucleic acids and ends with publishing the results and is organized to lead the reader through the whole process.