Name: Bone Marrow Niche: Microenvironments Critical for Immune Cell Development (en Inglés)
SKU: 54776267
Price: 140.37 USD
Availability: InStock
Author: Nagasawa, Takashi

portada Bone Marrow Niche: Microenvironments Critical for Immune Cell Development (en Inglés)

Bone Marrow Niche: Microenvironments Critical for Immune Cell Development (en Inglés)

Formato

Libro Físico

Ilustrado por

Takashi Nagasawa

Editorial

Springer

Autor

Nagasawa, Takashi

Idioma

Inglés

N° páginas

134

Encuadernación

Tapa Blanda

Dimensiones

23.4x15.6x0.8 cm

Peso

0.21 kg.

ISBN13

9783030860189

Categorías

Oncología
Inmunología
Biología celular (citología)

Bone Marrow Niche: Microenvironments Critical for Immune Cell Development (en Inglés)

Takashi Nagasawa (Ilustrado por) · Springer · Tapa Blanda

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Reseña del libro "Bone Marrow Niche: Microenvironments Critical for Immune Cell Development (en Inglés)"

This volume summarizes recent advances in research on mesenchymal cell populations in the bone marrow. It explores how mesenchymal cells create niches for immune cells in extramedullary organs and it discusses new concepts of lympho-hematopoietic microenvironments. Readers are introduced to the fundamentals of hematopoietic stem cells (HSCs) differentiation to all types of blood cells, including immune cells, in the bone marrow. The book highlights how this process is supported and regulated by the individual microenvironments of stem cells, termed niches.The identity of HSC niches has been subject to longstanding debates. Recent studies identified the population of mesenchymal stem cells as the major cellular component of niches, for hematopoietic stem and progenitor cells (HSPCs) and their candidate developmental origin. Furthermore, candidate cellular niches for immune cells in lymph nodes and adipose and connective tissues were identified. The authors of this volume focus on shared features between those and HSPC niche cells in the bone marrow. Covering latest research results, this book serves as fascinating read for researchers and clinicians in hematology and immunology.