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High-Throughput Screening Methods in Toxicity Testing (en Inglés)
Steinberg, Pablo (Autor)
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Wiley
· Tapa Dura
High-Throughput Screening Methods in Toxicity Testing (en Inglés) - Steinberg, Pablo
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Reseña del libro "High-Throughput Screening Methods in Toxicity Testing (en Inglés)"
this book describes the high - throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs. the book is divided into 5 parts: 1) general aspects; 2) high - throughput assays to assess different cytotoxicity endpoints 3) high - throughput assays to assess dna damage and carcinogenesis; 4) high - throughput assays to assess reproductive toxicity, cardiotoxicity, and hematoxicity; 5) high - throughput assays to assess drug metabolism and receptor related toxicity. each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. in addition to the advantages of the high - throughput over the conventional method, the chapters also point out limitations and pitfalls
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