Name: Sh Domains: Structure, Mechanisms and Applications (en Inglés)
SKU: 58471872
Price: 95.37 USD
Availability: InStock
Author: Kurochkina, Natalya

portada Sh Domains: Structure, Mechanisms and Applications (en Inglés)

Sh Domains: Structure, Mechanisms and Applications (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Kurochkina, Natalya

Idioma

Inglés

N° páginas

253

Encuadernación

Tapa Blanda

Dimensiones

23.4x15.6x1.4 cm

Peso

0.37 kg.

ISBN13

9783319372525

Categorías

Bioquímica
Biología molecular
Biología celular (citología)

Sh Domains: Structure, Mechanisms and Applications (en Inglés)

Kurochkina, Natalya (Autor) · Springer · Tapa Blanda

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Reseña del libro "Sh Domains: Structure, Mechanisms and Applications (en Inglés)"

This book covers structure, function, and important roles of the SH domains, structure-function relationships, the versatile nature of their action, mechanisms of aggregation, specificity of interactions, impact of mutations on protein functional dysregulation, and cell signaling. Their involvement in various cellular processes such as migration, invasiveness, actin reorganization, shaping spines, determination of the morphology assembly of fibrils, and mechanotransduction makes these molecules attractive drug targets. Substrates, inhibitors and activators of PTKs present a wide variety of therapeutic agents in the context of delivering treatments for numerous pathologies. The new emerging field of stem cell therapies and design of biomaterials for treatments relies on the directed regulation of stem cell growth, differentiation and morphology, as well as the production of biomimetic scaffolds that respond to programmed signals. Advances in deciphering the mechanisms of action of these important molecules will lead to the implementation and success of their vital applications.