portada Superficial bladder tumors (en Inglés)

Formato

Libro Físico

Autor

Sarra Ben Rejeb

Dorra Ben Gachem

Editorial

Our Knowledge Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x0.6 cm

Peso

0.15 kg.

ISBN13

9786207188970

Categorías

Medicina: cuestiones generales

Superficial bladder tumors (en Inglés)

Sarra Ben Rejeb (Autor) · Dorra Ben Gachem (Autor) · Our Knowledge Publishing · Tapa Blanda

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Reseña del libro "Superficial bladder tumors (en Inglés)"

Non-muscle-invasive bladder tumours (NMIBTs) are tumours with an unpredictable course. Endoscopic and histological prognostic factors have been identified, but remain insufficient, leading us to propose new molecular prognostic factors. 40 TVNIM were collected over a 6-year period (2008-2013), and immunohistochemical studies were carried out on E-cadherin, an intercellular adhesion molecule, and β-cathenin, a molecule associated with E-cadherin. An inverse correlation between E-cadherin on the one hand, and stage (p=0.001), grade (p=0.0000000), recurrence (p=0.0000000), progression (p=0.01), SSR (p=0.00000001) and PFS (p=0.01) on the other, was detected. There was also a correlation between beta-cathenin and stage (p=0.05), grade (p=0.02) and recurrence (p=0.02).The negativity of these two antibodies would make it possible to "screen" high-risk NMVTs, which could benefit from closer monitoring and/or more aggressive treatment.