Name: RNA Damage and Repair (en Inglés)
SKU: 57450688
Price: 147.13 USD
Availability: InStock
Author: Kotta-Loizou, Ioly

portada RNA Damage and Repair (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Kotta-Loizou, Ioly

Idioma

Inglés

N° páginas

178

Encuadernación

Tapa Blanda

Dimensiones

23.4x15.6x1 cm

Peso

0.27 kg.

ISBN13

9783030765736

Categorías

Bioquímica
Biología molecular
Ciencia de materiales

RNA Damage and Repair (en Inglés)

Kotta-Loizou, Ioly (Autor) · Springer · Tapa Blanda

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Reseña del libro "RNA Damage and Repair (en Inglés)"

Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems). Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.